Workshop

Redox Biology in Health and Disease

 

Barcelona, June 27-28th, 2024

Organizers: Victoria Campuzano, Gustavo Egea, Isabel Fabregat

PROGRAMREGISTRATION

Total: 150 participants

Thrusday 27th

08:30 – 09:00 Registration

09:00 – 09:30 Welcome

09:30 – 11:00 SESSION 1: ROLE OF MITOCHONDRIA IN THE REGULATION OF REDOX BIOLOGY-I. Chaired by: Joaquim Ros, Universitat de Lleida, Lleida, Spain.

  • Antonio Enríquez, Spanish National Center for Cardiovascular Research (CNIC) and CIBERFES, Madrid, Spain. “Redox communication through mitochondria”.
  • Antonio Zorzano, University of Barcelona and Institute for Research in Biomedicine and CIBEREDEM, Barcelona, Spain. “Mitochondrial fusion proteins and their role in cell homeostasis”.
  • Jose-Carlos Fernández-Checa, IDIBAPS, Barcelona Clinic Hospital and CIBEREHD, Barcelona, Spain.“Mitochondrial cholesterol trafficking in metabolic-associated steatohepatitis and liver cancer”.

11:00 – 11:30 Coffee Break

11:30 – 12:30 SESSION 2: ROLE OF MITOCHONDRIA IN THE REGULATION OF REDOX BIOLOGY-II. Chaired by: Elena Hidalgo, Universitat Pompeu Fabra, Barcelona, Spain.

  • M. Isabel Hernández-Álvarez, University of Barcelona, Barcelona, Spain. “Mitochondrial fusion proteins and organelle connections in metabolism”.
  • Juan Pedro Bolaños, University of Salamanca and CIBERFES, Salamanca, Spain. “Astrocyte metabolism: energy or signaling?”.

12:30 – 13:30 OPENING KEYNOTE LECTURE. Chaired by: Gustavo Egea, Universitat de Barcelona, Barcelona, Spain.

  • Victor Thannickal, Tulane University School of Medicine, New Orleans, USA). “From Oxygen to Redox Biology and Organ Regeneration”

13:30 – 15:00 Lunch

15:00 – 16:30 SESSION 3: REDOX BIOLOGY IN INFLAMMATION AND NEUROLOGICAL DISEASES. Chaired by: Teresa Carbonell, Universitat de Barcelona, Barcelona, Spain.

  • Gemma Marfany, University of Barcelona and CIBERER, Barcelona, Spain. “Bringing light to darkness: CERKL, a retinal resilience gene against oxidative stress”.
  • Joaquim Ros, University of Lleida, Lleida, Spain Alterations of mitochondrial function in Friedreich’s Ataxia”.
  • Juan Sastre, University of Valencia, Valencia, Spain. President of the SFRR-Europe. “TRP14 regulates intracellular cystine reduction and protein cysteinylation”.

Friday 28th

08:30 – 09:00 Registration

09:30 – 11:00 SESSION 4: REDOX SIGNALLING IN CARDIOVASCULAR PATHOLOGIES. Chaired by: Victoria Campuzano, Universitat de Barcelona, Barcelona, Spain.

  • Susana Cadenas, Center of Molecular Biology Severo Ochoa – CBMSO (CSIC/UAM), Madrid, Spain. “Redox signaling and cardioprotection in ischemia-reperfusion injury”.
  • Vivian de Waard, Amsterdam University Medical Center (AUMC), University of Amsterdam, Amsterdam, The Netherlands: “Resveratrol as antioxidant therapy in aortic disease in Marfan syndrome”.
  • María Galán, University Rey Juan Carlos (URJC), Madrid, Spain. “Targeting mitochondrial stress to limit aortic dilation in murine models of aneurysm”.

11:00 – 11:30 Coffee Break

11:30 – 12:30 SESSION 5: NEW INSIGTHS ABOUT NADPH OXIDASES AS THERAPEUTIC TARGETS IN HUMAN DISEASES. Chaired by: Juan Sastre. University of Valencia, Valencia, Spain. President of the SFRR-Europe.

  • Susan M.E. Smith, Kennesaw State University, Kennesaw, Georgia, USA. “Comparison of NOX structures suggests potential new druggable site(s)”.
  • Miklós Geiszt, Semmelweis University, Medical School, Budapest, Hungary. “Lessons from the rabbit model of NOX5 deficiency”.

12:30 – 13:30 CLOSING KEYNOTE LECTURE. Chaired by: Isabel Fabregat, IDIBELL and CIBEREHD, Barcelona, Spain.

  • Ulla Knaus, School of Medicine, University College Dublin, Dublin, Ireland. “NADPH oxidase: culprit and protector in the intestine”.

13:30 – 14:00 CONCLUDING REMARKS.